| Product Name | RLBP1, 1-317aa, Human, Baculovirus |
|---|---|
| Description | RLBP1, as known as retinaldehyde binding protein 1, is a soluble protein. It participates in the regeneration of active 11-cis-retinol and 11-cis-retinaldehyde, from the inactive 11-trans products of the rhodopsin photocycle and in the de novo synthesis of these retinoids from 11-trans metabolic precursors. The cycling of retinoids between photoreceptor and adjacent pigment epithelium cells is known as the 'visual cycle'. Recombinant human RLBP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Synonyms | Retinaldehyde binding protein 1 , RLBP1, CRALBP, Cellular retinaldehyde binding protein like, CRALBPL, FLJ37248, Retinaldehyde binding protein 1 like 1, RLBP1L1 |
| Host | Virus |
| Molecular Weight |
41.4kDa (370aa) 40-57KDa (SDS-PAGE under reducing conditions) |
| Amino Acid Sequence | ADPMSEGVGT FRMVPEEEQE LRAQLEQLTT KDHGPVFGPC SQLPRHTLQK AKDELNEREE TREEAVRELQ EMVQAQAASG EELAVAVAER VQEKDSGFFL RFIRARKFNV GRAYELLRGY VNFRLQYPEL FDSLSPEAVR CTIEAGYPGV LSSRDKYGRV VMLFNIENWQ SQEITFDEIL QAYCFILEKL LENEETQING FCIIENFKGF TMQQAASLRT SDLRKMVDML QDSFPARFKA IHFIHQPWYF TTTYNVVKPF LKSKLLERVF VHGDDLSGFY QEIDENILPS DFGGTLPKYD GKAVAEQLFG PQAQAENTAF HHHHHH |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate Buffered Saline (pH 7.4) containing 10% glycerol, 1mM DTT |
| Concentration | 0.25mg/ml (determined by Absorbance at 280nm) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Neutzner RV., et al. (2011) Ophthalmologe 108:1045-1049. Intres R., et al. (1994) J. Biol. Chem. 269:25411-25418. |
| Background | RLBP1, as known as retinaldehyde binding protein 1, is a soluble protein. It participates in the regeneration of active 11-cis-retinol and 11-cis-retinaldehyde, from the inactive 11-trans products of the rhodopsin photocycle and in the de novo synthesis of these retinoids from 11-trans metabolic precursors. The cycling of retinoids between photoreceptor and adjacent pigment epithelium cells is known as the 'visual cycle'. Recombinant human RLBP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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