| Product Name | RPA1 Monoclonal Antibody |
|---|---|
| Description | Mouse monoclonal antibody to RPA1 |
| Synonyms | Dmrpa1; Drosophila Replication Protein A; DRPA; HSSB; Human single stranded DNA binding protein; MST075; MSTP075; p70; REPA1; Replication factor A; Replication factor A protein 1; Replication protein A 70 kDa DNA-binding subunit; |
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Immunogen | Purified recombinant human RPA70 protein fragments expressed in E.coli. |
| Isotype | IgG2a |
| Target | RPA1 |
| Specificity | This antibody detects endogenous levels of RPA70 and does not cross-react with related proteins. |
| Reactivity | Monkey, Human, Mouse, Rat |
| Applications | ELISA, ICC, IP, WB |
| Form | liquid |
| Diluent Buffer | Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol. |
| Uniprot | P27694 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Plays an essential role in several cellular processes in DNA metabolism including replication,recombination and DNA repair.Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing.Functions as component of the alternative replication protein A complex (aRPA).aRPA binds single-stranded DNA and probably plays a role in DNA repair;it does not support chromosomal DNA replication and cell cycle progression through S-phase.In vitro,aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC),the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange |
| Supplier | Cusabio |
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