RPS7, 1-194aa, Human

Category: Proteins
Catalog
01-2193-7
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Product Name RPS7, 1-194aa, Human
Description RPS7 belongs to the S3P family of ribosomal proteins and is located in the cytoplasm. RPS7 may play a role in ribosomal stress, linking ribosome biogenesis to cell death or cell cycle arrest. Also, RPS7 interacts with MDM2 and is believed to negatively regulate the MDM2-mediated degradation of p53. Recombinant human RPS7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms 40S ribosomal protein S7, DBA8, S7
Host E. coli
Molecular Weight 24.1 kDa (217aa), confirmed by MALDI-TOF
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSHMFSSSA KIVKPNGEKP DEFESGISQA LLELEMNSDL KAQLRELNIT AAKEIEVGGG RKAIIIFVPV PQLKSFQKIQ VRLVRELEKK FSGKHVVFIA QRRILPKPTR KSRTKNKQKR PRSRTLTAVH DAILEDLVFP SEIVGKRIRV KLDGSRLIKV HLDKAQQNNV EHKVETFSGV YKKLTGKDVN FEFPEFQL
Tag His-tag
Reactivity Human
Applications SDS-PAGE
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.2M NaCl
Concentration 0.5 mg/ml (determined by Bradford assay)
Purity > 90% by SDS-PAGE
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles.
References Malygin AA., et al. (2000) Buichim Biophys Acta. 1494:213-216. Hosaka H., et al. (2001) J Biochem. 130:695-701.
Background RPS7 belongs to the S3P family of ribosomal proteins and is located in the cytoplasm. RPS7 may play a role in ribosomal stress, linking ribosome biogenesis to cell death or cell cycle arrest. Also, RPS7 interacts with MDM2 and is believed to negatively regulate the MDM2-mediated degradation of p53. Recombinant human RPS7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Supplier ARP

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