| Product Name | RRM1 Monoclonal Antibody |
|---|---|
| Description | Mouse monoclonal antibody to RRM1 |
| Synonyms | Ribonucleotide Reductase M1,RRM1,RR1 |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 3D6H5 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human RRM1 Protein |
| Isotype | IgG |
| Target | RRM1 |
| Specificity | specific for human RRM1 denatured and native forms. |
| Reactivity | Human |
| Applications | ELISA, IHC |
| Form | liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot | P23921 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells.It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor,rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. |
| Supplier | Cusabio |
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