| Product Name | S100A9, 1-114aa, Human |
|---|---|
| Description | S100-A9, also known as Calgranulin B, belongs to the S100 family containing EF-hand type Ca2+-binding proteins. It is involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation, and associated with the disease cystic fibrosis. S100A9 has been implicated in the abnormal differentiation of myeloid cells in the stroma of cancer. This protein may function in the inhibition of casein kinase. Recombinant S100A9 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Synonyms | Calgranulin B, 60B8AG, CAGB, CFAG, CGLB, L1AG, LIAG, MAC387, MIF, MRP14, NIF, P14, Protein S100-A9 AI323541, B8Ag, BEE11, CAGA, Calgranulin-A, Calprotectin L1L subunit, Calprotectin, included, CGLA, Chemotactic cytokine CP-10, CP-10, Cystic fibrosis antigen, Leukocyte L1 complex light chain MA387, MIF, Migration inhibitory factor-related protein 8, Myeloid-related protein 8, Neutrophil cytosolic 7 kDa protein, NIF, p8, Pro-inflammatory S100 cytokine, Protein S100-A8, S100 calcium binding protein A8, S100 calcium binding protein A8 (calgranulin A), S100A8, S100A8/S100A9 complex, included, Urinary stone protein band A. |
| Host | E. coli |
| Molecular Weight | 18.2 kDa (154aa), confirmed by MALDI-TOF |
| Amino Acid Sequence | MTCKMSQLER NIETIINTFH QYSVKLGHPD TLNQGEFKEL VRKDLQNFLK KENKNEKVIE HIMEDLDTNA DKQLSFEEFI MLMARLTWAS HEKMHEGDEG PGHHHKPGLG EGTPLEHHHH HH |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20 mM Tris-HCl buffer (pH8.0) containing 2mM DTT, 0.1M NaCl, 20% glycerol |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Schäfer BW. et al. (1996) Trends Biochem Sci. 21(4):134-40. Nacken W,.et al. (2003) Microsc Res Tech. 60(6):569-80. |
| Background | S100-A9, also known as Calgranulin B, belongs to the S100 family containing EF-hand type Ca2+-binding proteins. It is involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation, and associated with the disease cystic fibrosis. S100A9 has been implicated in the abnormal differentiation of myeloid cells in the stroma of cancer. This protein may function in the inhibition of casein kinase. Recombinant S100A9 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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