| Product Name | S100B Monoclonal Antibody |
|---|---|
| Description | Mouse monoclonal antibody to Protein S100B |
| Synonyms | S100B ,S-100 protein beta chain,S-100 protein subunit beta,S100 calcium-binding protein B |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 1A1B1 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human S100B protein |
| Isotype | IgG1 |
| Target | S100B |
| Specificity | specific for S100B native and denatured forms |
| Reactivity | Human |
| Applications | ELISA |
| Form | liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot | P04271 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity. |
| Supplier | Cusabio |
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