SAMS Peptide

Category: Bioreagents
Catalog
KS-020
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Product Name SAMS Peptide
Description SAMS peptide is a substrate for AMP-activated protein kinase (AMPK). Phosphorylated rapidly by AMPK, the Km of AMP-activated protein kinase for the SAMS peptide is higher than that for acetyl-CoA carboxylase, but the Vmax for peptide phosphorylation is 2.5 times higher than that of the parent protein. SAMS peptide therefore gives a convenient and sensitive assay for AMPK
Synonyms AMP-activated protein kinase, AMPK, HMRSAMSGLHLVKRR, KS-020, KS020, SAMS peptide, assay, substrate
Molecular Weight 1780 Da
Target Kinases
Amino Acid Sequence HMRSAMSGLHLVKRR
Form Freeze dried solid
Purity >95% by HPLC
Cas Number 125911-68-4
Storage Store dark, frozen and desiccated
Notes Modifications: None
References Carling et al (1989) Purification and characterization of the AMP-activated protein kinase. Eur.J.Biochem. 186 129 PMID: 2598924Davies et al (1989) Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP-dependent protein kinase, studied using a specific and sensitive peptide assay. Eur.J.Biochem. 186 123 PMID: 2574667Dasgupta et al (2012) The AMPK β2 subunit is required for energy homeostasis during metabolic stress. Mol. Cell. Biol. 32(14) 2837 PMID: 22586267
Related areas
All kinase modulators >All substrate peptides >
Supplier Isca Biochemicals Limited

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