| Product Name | Saralasin |
|---|---|
| Description | Saralasin, also known as [Sar1,Val5, Ala8] angiotensin II is an angiotensin II analog with substitutions to the angiotensin II sequence of sarcosine at position 1, valine at position 5,and alanine at position 8. Saralasin is a partial agonist of the angiotensin II receptor, and is used to treat hypertension. |
| Synonyms | [Sar1,Val5, Ala8] angiotensin II |
| Molecular Weight | 912 Da |
| Target | Angiotensin receptors |
| Amino Acid Sequence | XRVYVHPA |
| Form | Freeze dried solid |
| Purity | >95% by HPLC |
| Cas Number | 34273-10-4 |
| Storage | Store desiccated, frozen and in the dark |
| Notes | Modifications: X = Sarcosine |
| References |
Steinhausen et al (1986) Angiotensin II control of the renal microcirculation: effect of blockade by saralasin. Kidney Int. 30 56 PMID: 3747343Thomas et al (1995) Saralasin suppresses arrhythmias in an isolated guinea-pig ventricular free wall model of simulated ischemia and reperfusion. J.Pharmacol.Exp.Ther. 274 1379 PMID: 7562511Guimond et al (2014) Saralasin and Sarile Are AT2 Receptor Agonists. ACS Med. Chem. Lett. 5(10) 1129 PMID: 25313325 Related areas All peptides > All angiotensin receptor modulators >All endocrinology research categories >All cardiovascular research categories > |
| Supplier | Isca Biochemicals Limited |
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