| Product Name | SDSL, 1-329aa, Human |
|---|---|
| Description | SDSL (serine dehydratase-like) is like L-serine dehydratase, uses pyridoxal phosphate. L-serine dehydratase, known simply as serine dehydratase (SDS), is one of three main enzymes that are involved in the metabolism of Glycine and serine. One of several members of the serine/threonine dehydratase family, SDSL may function as a serinespecific dehydratase that plays a role in protein metabolism. It has low serine dehydratase and threonine dehydratase activity. Recombinant human SDSL protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Synonyms | Serine dehydratase-like, SDH 2, SDS-RS1, TDH |
| Host | E. coli |
| Molecular Weight | 37.9 kDa (353aa) |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSHMDGPVA EHAKQEPFHV VTPLLESWAL SQVAGMPVFL KCENVQPSGS FKIRGIGHFC QEMAKKGCRH LVCSSGGNAG IAAAYAARKL GIPATIVLPE STSLQVVQRL QGEGAEVQLT GKVWDEANLR AQELAKRDGW ENVPPFDHPL IWKGHASLVQ ELKAVLRTPP GALVLAVGGG GLLAGVVAGL LEVGWQHVPI IAMETHGAHC FNAAITAGKL VTLPDITSVA KSLGAKTVAA RALECMQVCK IHSEVVEDTE AVSAVQQLLD DERMLVEPAC GAALAAIYSG LLRRLQAEGC LPPSLTSVVV IVCGGNNINS RELQALKTHL GQV |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH 8.0) 1M Urea, 5% Glycerol. |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Yamada T., et al. (2008) Biochim. Biophys. Acta 1780:809-818 Xue, H.H., et al. (1999) J. Biol. Chem. 274: 16028-16033. |
| Background | SDSL (serine dehydratase-like) is like L-serine dehydratase, uses pyridoxal phosphate. L-serine dehydratase, known simply as serine dehydratase (SDS), is one of three main enzymes that are involved in the metabolism of Glycine and serine. One of several members of the serine/threonine dehydratase family, SDSL may function as a serinespecific dehydratase that plays a role in protein metabolism. It has low serine dehydratase and threonine dehydratase activity. Recombinant human SDSL protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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