| Product Name | SEC5/EXOC2 Monoclonal Antibody |
|---|---|
| Description | EXOC2 (exocyst complex component 2),also known as SEC5 and SEC5L1,is a component of the exocyst complex,and is required to mediate RalB-dependent survival signals in transformed cells. The exocyst complex,composed of eight evolutionarily conserved subunits (SEC3,SEC5,SEC6,SEC8,SEC10,SEC15,EXO70,and EXO84),is involved in tethering post-Golgi secretory vesicles to specific plasma membrane domains. The gene of EXOC2 maps to chromosome 6p25.3,and encodes a 924-amino acid protein with an experimentally determined molecular mass of 95-100 kDa. EXOC2 mRNA is widely expressed with highest levels in brain and placenta. |
| Synonyms | EXOC2,exocyst complex component 2,Exocyst complex component Sec5,FLJ11026,SEC5,SEC5L1,Sec5p |
| Host | Mouse |
| Clone | 346 |
| Immunogen | Fusion protein of SEC5/EXOC2 |
| Isotype | IgG2b |
| Reactivity | Human, Mouse |
| Applications | ELISA, IF, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | Q96KP1 |
| Background | EXOC2 (exocyst complex component 2),also known as SEC5 and SEC5L1,is a component of the exocyst complex,and is required to mediate RalB-dependent survival signals in transformed cells. The exocyst complex,composed of eight evolutionarily conserved subunits (SEC3,SEC5,SEC6,SEC8,SEC10,SEC15,EXO70,and EXO84),is involved in tethering post-Golgi secretory vesicles to specific plasma membrane domains. The gene of EXOC2 maps to chromosome 6p25.3,and encodes a 924-amino acid protein with an experimentally determined molecular mass of 95-100 kDa. EXOC2 mRNA is widely expressed with highest levels in brain and placenta. |
| Supplier | Elabscience |
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