[Ser159]-PKCε (149-164)

Category: Bioreagents
Catalog
KS-090
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Product Name [Ser159]-PKCε (149-164)
Description [Ser159]-PKCε (149-164) is a protein kinase C epsilon (PKCε) pseudosubstrate with a serine substituted for an alanine at ser159. This substitution allows [Ser159]-PKCε (149-164) to be phosphorylated by PKC and this allows [Ser159]-PKCε (149-164) to be a phospholipid/phorbol ester-dependent substrate for PKC ε, ζ, δ and η.
Synonyms Protein kinase C epsilon (PKCε) (149-164) pseudosubstrate
Molecular Weight 2066.2 Da
Target Kinases
Amino Acid Sequence ERMRPRKRQGSVRRRV
Form Freeze dried solid
Purity >95% by HPLC
Storage Store desiccated, frozen and in the dark
Notes Modifications: None
References Nakanishi et al (1993) Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 268 13 PMID: 8380153Lee (2011) The role of atypical protein kinase C in CSF-1-dependent Erk activation and proliferation in myeloid progenitors and macrophages. PLoS One 6(10) e25580 PMID: 22028782
Related data
All kinase modulators >All substrate peptides >
Supplier Isca Biochemicals Limited

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