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|Product Name||SERTAD2, 1-314aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGSMLGKGGK RKFDEHEDGL EGKIVSPCDG PSKVSYTLQR QTIFNISLMK LYNHRPLTEP SLQKTVLINN MLRRIQEELK QEGSLRPMFT PSSQPTTEPS DSYREAPPAF SHLASPSSHP CDLGSTTPLE ACLTPASLLE DDDDTFCTSQ AMQPTAPTKL SPPALLPEKD SFSSALDEIE ELCPTSTSTE AATAATDSVK GTSSEAGTQK LDGPQESRAD DSKLMDSLPG NFEITTSTGF LTDLTLDDIL FADIDTSMYD FDPCTSSSGT ASKMAPVSAD DLLKTLAPYS SQPVTPSQPF KMDLTELDHI MEVLVGS|
|Background||SERTA domain containing 2, also known as SERTAD2, acts at E2F-responsive promoters to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Recombinant human SERTAD2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
|Concentration||0.5 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT|
|Intended Use||For Research Use Only|
|Molecular Weight||30.0 kDa (270aa), confirmed by MALDI-TOF|
|NCBI Accession #||NP_055570|
|Purity||> 90% by SDS-PAGE|
|References||Cheong J.K., et al. (2009) J Transl Med. 7:8-8
Liew C.W., et al. (2013) Nat. Med. 19:217-226
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||SERTA domain containing 2, Sei-2, TRIP-Br2|
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