Product Name | SIGIRR Antibody |
---|---|
Description | Rabbit polyclonal antibody to SIGIRR |
Synonyms | Ig IL1 related receptor antibody; MGC110992 antibody; SIGIR_HUMAN antibody; SIGIRR antibody; Single Ig IL 1 related receptor antibody; Single Ig IL-1-related receptor antibody; Single Ig IL-1R-related molecule antibody; Single Ig IL1R Related Molecule antibody; Single immunoglobulin and toll interleukin 1 receptor (TIR) domain antibody; Single immunoglobulin and toll interleukin 1 receptor domain antibody; Single immunoglobulin domain containing IL1R related protein antibody; Single immunoglobulin domain IL1R1 related antibody; Single immunoglobulin domain-containing IL1R-related protein antibody; TIR 8 antibody; TIR8 antibody; Toll/interleukin 1 receptor 8 antibody; Toll/interleukin-1 receptor 8 antibody |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Unconjugated |
Immunogen | Recombinant human Single Ig IL-1-related receptor protein (1-120AA) |
Isotype | IgG |
Target | SIGIRR |
Reactivity | Human, Mouse |
Applications | ELISA, IHC, WB |
Form | Liquid |
Diluent Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Uniprot | Q6IA17 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Background | Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP. |
Supplier | Cusabio |
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