| Product Name | Slo3 Antibody: ATTO 633 |
|---|---|
| Description | The Slo3 channel is a novel potassium channel abundantly expressed in mammalian speramtocytes- tests have shown that it is expressed in both mouse and human testis (3). It represents a new and unique type of potassium channel that is regulated by both intracellular pH and membrane voltage (1). Because of its sensitivity to both pH and voltage, Slo3 may play a role in alkalization-mediated K(+) fluxes associated with sperm capacitation (2). . Mouse Anti-Mouse Slo3 Monoclonal IgG2b |
| Synonyms | Kcnma3 Antibody, mSlo3 Antibody, Slo3 Antibody, KCa5 Antibody, KCNMA3 Antibody, potassium channel subfamily U member 1 Antibody, Slowpoke homolog 3 Antibody, KCa5.1 Antibody, KCNMC1Calcium-activated potassium channel Antibody, subfamily M subunit alpha-3 |
| Host | Mouse |
| Clone | S2-16 |
| Immunogen | Fusion protein amino acids 1052-1121 of mouse Slo3 |
| Isotype | IgG2b |
| Specificity | Detects ~115kDa. |
| Reactivity | Human, Mouse, Rat |
| Applications | AM, ICC, IF, IHC, WB |
| Form | Purified, in PBS pH7.4, 50% glycerol, 0.09% sodium azide |
| Gene Id | NP_032458.3. 16532 |
| Uniprot | O54982 |
| Background |
The Slo3 channel is a novel potassium channel abundantly expressed in mammalian speramtocytes- tests have shown that it is expressed in both mouse and human testis (3). It represents a new and unique type of potassium channel that is regulated by both intracellular pH and membrane voltage (1). Because of its sensitivity to both pH and voltage, Slo3 may play a role in alkalization-mediated K(+) fluxes associated with sperm capacitation (2). |
| Supplier | Stressmarq Biosciences |
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