| Product Name | SMAP 29 (sheep) |
|---|---|
| Description | SMAP 29 (sheep) is a 29 amino acid sheep myeloid antimicrobial peptide (SMAP) which is a cathelicidin with an alpha helical structure and the ability to disrupt cell membranes. SMAP 29 (sheep) acts as a broad spectrum antimicrobial activity against gram negative and gram-positive bacteria and fungi and has been investigated as a treatment for acute and chronic respiratory infections. |
| Synonyms | Sheep myeloid antimicrobial peptide |
| Molecular Weight | 3256 Da |
| Target | Antibacterials,Antifungals |
| Amino Acid Sequence | RGLRRLGRKIAHGVKKYGPTVLRIIRIAG |
| Form | Freeze dried solid |
| Purity | >95% by HPLC |
| Storage | Store in the dark, frozen and desiccated |
| Notes | Modifications: None |
| References |
Kalfa et al (2001) Congeners of SMAP29 Kill Ovine Pathogens and Induce Ultrastructural Damage in Bacterial Cells. Antimicrob. Agents and Chemotherap. 45(11) 3256 PMID: 11600395Chang et al (2012) Outer membrane lipoprotein Lpp is Gram-negative bacterial cell surface receptor for cationic antimicrobial peptides. J Biol. Chem. 287(1) 418 PMID: 22084237Kao et al (2016) Cathelicidin Antimicrobial Peptides with Reduced Activation of Toll-Like Receptor Signaling Have Potent Bactericidal Activity against Colistin-Resistant Bacteria. mBio 7 (5) e01418 PMID: 27651360 Related areasAll antimicrobial peptides >All antifungal agents >All immunology research categories > |
| Supplier | Isca Biochemicals Limited |
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