| Product Name | SMARCD1 Monoclonal Antibody |
|---|---|
| Description | SMARCD1 (SWI/SNF related,matrix associated,actin dependent regulator of chromatin,subfamily d,member 1),also known as BAF60a (BRG1-associated factor 60A),Rsc6p or CRACD1,is a 476 amino acid protein that localizes to the nucleus and contains one SWIB domain. Expressed ubiquitously with notable expression in liver,brain,muscle, lung,kidney,pancreas and placenta,SMARCD1 functions as a component of the BAF complex and,in conjunction with a variety of other proteins,plays an essential role in chromatin remodeling. In addition,SMARCD1 influences vitamin D-mediated transcriptional activity and is thought to provide a link between the vitamin D receptor (VDR) and SWI/SNF chromatin remodeling complexes. Multiple isoforms of BAF60a exist due to alternative splicing events. |
| Synonyms | BAF60A,BRG1 associated factor 60A,CRACD1,Rsc6p,SMARCD1,SWI/SNF complex 60 kDa subunit |
| Host | Mouse |
| Clone | 224 |
| Immunogen | Fusion protein of SMARCD1 |
| Isotype | IgG1 |
| Reactivity | Human |
| Applications | ELISA, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | Q96GM5 |
| Background |
SMARCD1 (SWI/SNF related,matrix associated,actin dependent regulator of chromatin,subfamily d,member 1),also known as BAF60a (BRG1-associated factor 60A),Rsc6p or CRACD1,is a 476 amino acid protein that localizes to the nucleus and contains one SWIB domain. Expressed ubiquitously with notable expression in liver,brain,muscle, lung,kidney,pancreas and placenta,SMARCD1 functions as a component of the BAF complex and,in conjunction with a variety of other proteins,plays an essential role in chromatin remodeling. In addition,SMARCD1 influences vitamin D-mediated transcriptional activity and is thought to provide a link between the vitamin D receptor (VDR) and SWI/SNF chromatin remodeling complexes. Multiple isoforms of BAF60a exist due to alternative splicing events. |
| Supplier | Elabscience |
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