SNAI2, 1-268aa, Human

Category: Proteins
Catalog
01-P3078
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Product Name SNAI2, 1-268aa, Human
Description SNAI2 also known as Zinc finger protein SNAI2. This protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. SNAI2 is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Recombinant human SNAI2, fused to His-tag at N-terminus, was expressed in E.coli.
Synonyms Zinc finger protein SNAI2, SLUG, SLUGH1, SNAIL2, WS2D
Host E. coli
Molecular Weight 29.1kDa (251aa) confirmed by MALDI-TOF
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMPRSFLV KKHFNASKKP NYSELDTHTV IISPYLYESY SMPVIPQPEI LSSGAYSPIT VWTTAAPFHA QLPNGLSPLS GYSSSLGRVS PPPPSDTSSK DHSGSESPIS DEEERLQSKL SDPHAIEAEK FQCNLCNKTY STFSGLAKHK QLHCDAQSRK SFSCKYCDKE YVSLGALKMH IRTHTLPCVC KICGKAFSRP WLLQGHIRTH TGEKPFSCPH CNRAFADRSN LRAHLQTHSD VKKYQCKNCS KTFSRMSLLH KHEESGCCVA H
Tag His-tag
Reactivity Human
Applications SDS-PAGE
Form Liquid, Liquid, in Phosphate buffered saline (pH7.4) containing 20% glycerol, 1mM DTT
Concentration 1mg/ml (determined by Bradford assay)
Purity > 80% by SDS-PAGE
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles.
References Sinani D., et al. (2013) J. Virol. 87 (23), 13042-13047
Background SNAI2 also known as Zinc finger protein SNAI2. This protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. SNAI2 is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Recombinant human SNAI2, fused to His-tag at N-terminus, was expressed in E.coli.
Supplier ARP

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