| Product Name | SND1 Monoclonal Antibody |
|---|---|
| Description | Staphylococcal nuclease domain-containing 1 (SND1),is a multifunctional nuclease that consists of four staphylococcal nuclease domains and a tudor domain. SND1 acts as a coactivator that facilitates transcriptional activity of STAT5,6 and c-Myc. SND1 is a comprising part of the RNA-induced silencing complex(RISC),and takes part in the functions of miRNA,regulates transcription through transcriptional coactivation,RNA interference,RNA splicing,and RNA editing. Higher level of SND1 has been found in colon cancer and prostate cancer,can promote HCC angiogenesis in xenograft model through induction of angiogenic factors. |
| Synonyms | 100 kDa coactivator,EBNA2 coactivator p100,p100,p100 co activator,SND1,TDRD11 |
| Host | Mouse |
| Clone | 611 |
| Immunogen | Fusion protein of SND1 |
| Isotype | IgG1 |
| Reactivity | Human, Mouse |
| Applications | ELISA, IF, IHC, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | Q7KZF4 |
| Background | Staphylococcal nuclease domain-containing 1 (SND1),is a multifunctional nuclease that consists of four staphylococcal nuclease domains and a tudor domain. SND1 acts as a coactivator that facilitates transcriptional activity of STAT5,6 and c-Myc. SND1 is a comprising part of the RNA-induced silencing complex(RISC),and takes part in the functions of miRNA,regulates transcription through transcriptional coactivation,RNA interference,RNA splicing,and RNA editing. Higher level of SND1 has been found in colon cancer and prostate cancer,can promote HCC angiogenesis in xenograft model through induction of angiogenic factors. |
| Supplier | Elabscience |
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