| Product Name | Somatostatin 14 |
|---|---|
| Description |
Somatostatin, also known as growth hormone inhibiting hormone, is an endogenous peptide hormone. Somatostatin has two active forms produced by the alternative cleavage of a single preproprotein, one consisting of 14 amino acids, the other consisting of 28 amino acids. Somatostin 14 is the shorter isoform and works primarily in the brain, while the 28 amino acid form acts in the GI tract. Somatostatin 14 regulates the endocrine system and affects neurotransmission and cell proliferation though interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones. |
| Synonyms | Somatostatin; Growth hormone inhibiting hormone, SRIF 14 |
| Molecular Weight | 1637.88 Da |
| Target | Somatostatin receptors |
| Amino Acid Sequence | AGCKNFFWKTFTSC |
| Form | Freeze dried solid |
| Purity | >95% by hplc |
| Cas Number | 51110-01-1 |
| Storage | Store dry, frozen and in the dark |
| Notes | Modifications: Disulfide bridge between cysteine 3 and cysteine 14 |
| References |
Dileepan et al (1985) Somatostatin: a metabolic regulator. Life Sci. 37 2335 PMID: 2867445Günther et al (2018) Pharmacological Reviews 70(4) 763 DOI: https://doi.org/10.1124/pr.117.015388O'Toole and Sharma S. (2021) Physiology, Somatostatin. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2021 Jan https://www.ncbi.nlm.nih.gov/books/NBK538327/ Related areas All peptides >All somatostatin receptor modulators >All endocrinology research areas >All neuroscience research areas > |
| Supplier | Isca Biochemicals Limited |
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