| Product Name | STMN3 Monoclonal Antibody |
|---|---|
| Description | Stathmin family phosphoproteins participate in the control of microtubule dynamics and have been proposed to be involved in the control of neuronal differentiation. Neuron specific Stathmin-3 (STMN3) is a novel STAT3 (signal transducer and activator of transcription 3) interacting protein. STAT3 is a key contributor to cancer cell migration and invasion. STMN3 exhibits microtubule-destabilizing activity,which is antagonized by STAT3. SCG10 is a widely studied and recognized neuronal differentiation marker,STMN3 is a SCG10-like protein (SCLIP) and is present from the earliest stages of hippocampal neuron differentiation in culture at vesicle-like structures following dynamic microtubules. RNAi mediated inhibition of this gene resulted in increased axonal branching. |
| Synonyms | SCG10 like protein,SCLIP,Stathmin 3,stathmin like 3,STMN3 |
| Host | Mouse |
| Clone | 55 |
| Immunogen | Fusion protein of STMN3 |
| Isotype | IgG2b |
| Reactivity | Human |
| Applications | ELISA, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | Q9NZ72 |
| Background | Stathmin family phosphoproteins participate in the control of microtubule dynamics and have been proposed to be involved in the control of neuronal differentiation. Neuron specific Stathmin-3 (STMN3) is a novel STAT3 (signal transducer and activator of transcription 3) interacting protein. STAT3 is a key contributor to cancer cell migration and invasion. STMN3 exhibits microtubule-destabilizing activity,which is antagonized by STAT3. SCG10 is a widely studied and recognized neuronal differentiation marker,STMN3 is a SCG10-like protein (SCLIP) and is present from the earliest stages of hippocampal neuron differentiation in culture at vesicle-like structures following dynamic microtubules. RNAi mediated inhibition of this gene resulted in increased axonal branching. |
| Supplier | Elabscience |
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