| Product Name | STOM, 55-288aa, Human |
|---|---|
| Description | Erythrocyte band 7 integral membrane protein isoform a, also known as STOM, is a member of a highly conserved family of integral membrane proteins. STOM may regulate ACCN1 and ACCN3 gating. It is a membrane protein involved in regulation of monovalent cation transport through lipid membranes. A second function of STOM may be to act as a cytoskeletal anchor. It is a major lipid-raft component of erythrocytes and epithelial cells, and is also an abundant platelet protein. Recombinant human STOM protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Synonyms | Erythrocyte band 7 integral membrane protein isoform a, BND7, EPB7, EPB72 |
| Host | E. coli |
| Molecular Weight | 14.8kDa (133aa), confirmed by MALDI-TOF |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSKIIKEYE RAIIFRLGRI LQGGAKGPGL FFILPCTDSF IKVDMRTISF DIPPQEILTK DSVTISVDGV VYYRVQNATL AVANITNADS ATRLLAQTTL RNVLGTKNLS QILSDREEIA HNMQSTLDDA TDAWGIKVER VEIKDVKLPV QLQRAMAAEA EASREARAKV IAAEGEMNAS RALKEASMVI TESPAALQLR YLQTLTTIAA EKNSTIVFPL PIDMLQGIIG AKHSHLG |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH 7.5) containing 0.15M NaCl, 10% glycerol, 1mM DTT |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Mairhofer M., et al. (2002) Blood. 100:897-904. |
| Background | Erythrocyte band 7 integral membrane protein isoform a, also known as STOM, is a member of a highly conserved family of integral membrane proteins. STOM may regulate ACCN1 and ACCN3 gating. It is a membrane protein involved in regulation of monovalent cation transport through lipid membranes. A second function of STOM may be to act as a cytoskeletal anchor. It is a major lipid-raft component of erythrocytes and epithelial cells, and is also an abundant platelet protein. Recombinant human STOM protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Supplier | ARP |
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