| Product Name | STX1A, 1-265aa, Human |
|---|---|
| Description | STX1A, also as known as syntaxin 1A, is a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones. This protein plays a role in hormone and neurotransmitter exocytosis and may mediate Ca2+-regulation of exocytosis acrosomal reaction in sperm. Recombinant human STX1A was expressed in E.coli and purified by using conventional chromatography techniques. |
| Synonyms | Syntaxin 1A , HPC-1, P35-1, STX1, SYN1A,, Neuron specific antigen HPC1, Neuron-specific antigen HPC-1 OTTHUMP00000174615, OTTHUMP00000174616 OTTHUMP00000174617, OTTHUMP00000174618 P35-1, STX1, STX1A, STX1A_HUMAN, SYN1A Syntaxin 1A (brain), Syntaxin 1A brain, Syntaxin-1A |
| Host | E. coli |
| Molecular Weight | 36.6kDa (334aa) confirmed by MALDI-TOF |
| Amino Acid Sequence | MKDRTQELRT AKDSDDDDDV AVTVDRDRFM DEFFEQVEEI RGFIDKIAEN VEEVKRKHSA ILASPNPDEK TKEELEELMS DIKKTANKVR SKLKSIEQSI EQEEGLNRSS ADLRIRKTQH STLSRKFVEV MSEYNATQSD YRERCKGRIQ RQLEITGRTT TSEELEDMLE SGNPAIFASG IIMDSSISKQ ALSEIETRHS EIIKLENSIR ELHDMFMDMA MLVESQGEMI DRIEYNVEHA VDYVERAVSD TKKAVKYQSK ARRKK |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl (pH 8.0) containing 10% glycerol, 1mM DTT |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Purity | > 95% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Han X., et al. (2004) Science. 304:289-92 Woodbury DJ. et al. (2000) Cell Biology International. 24(11):809-18 |
| Background | STX1A, also as known as syntaxin 1A, is a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones. This protein plays a role in hormone and neurotransmitter exocytosis and may mediate Ca2+-regulation of exocytosis acrosomal reaction in sperm. Recombinant human STX1A was expressed in E.coli and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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