Product Name | sulA Antibody, Biotin conjugated |
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Description | Rabbit polyclonal antibody against sulA conjugated to Biotin. |
Synonyms | sulA antibody; sfiA antibody; b0958 antibody; JW0941 antibody; Cell division inhibitor SulA antibody |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Biotin |
Immunogen | Recombinant Escherichia coli Cell division inhibitor SulA protein (1-169AA) |
Isotype | IgG |
Target | sulA |
Reactivity | E. coli |
Applications | ELISA |
Form | Liquid |
Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Uniprot | P0AFZ5 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Background | Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. The effect of overexpression of SulA is neutralized by antitoxin CbeA (yeeU) (PubMed:22515815). |
Supplier | Cusabio |
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