| Product Name | SUMO-1, 1-97aa, Human, Recombinant |
|---|---|
| Description | SUMO-1, also known as small ubiquitin-related modifier 1, is a member of the SUMO protein family and functions in a manner similar to ubiquitin. However, unlike ubiquitin which targets proteins for degradation, SUMO-1 protein participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. Recombinant human SUMO1 protein was expressed in E.coli and purified by using conventional chromatography. |
| Synonyms | SMT3 suppressor of mif two 3 homolog 1 isoform a, DAP-1, GMP1, OFC10, PIC1, SENP2, SMT3, SMT3C, SMT3H3, UBL1, SMT3 suppressor of mif two 3 homolog 1 isoform a GAP modifying protein 1, GMP 1, PIC 1, Sentrin, Sentrin 1, Small ubiquitin related modifier 1, SMT3 homolog 3, UBL 1, SMT3 suppressor of mif two 3 homolog 1, Sumo1, Ubiquitin homology domain protein PIC1, Ubiquitin Like 1, Ubiquitin like protein SMT3C, Ubiquitin like protein UBL1. |
| Host | E. coli |
| Molecular Weight | 27 kDa (240aa), confirmed by MALDI-TOF. |
| Amino Acid Sequence | MSDQEAKPST EDLGDKKEGE YIKLKVIGQD SSEIHFKVKM TTHLKKLKES YCQRQGVPMN SLRFLFEGQR IADNHTPKEL GMEEEDVIEV YQEQTGG |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| Purity | > 95% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Evdokimov E., et al. (2008), J Cell Sci, 121:4106-13. Hecker CM., et al. (2006). J Biol Chem. 281(23):16117-27. |
| Background | SUMO-1, also known as small ubiquitin-related modifier 1, is a member of the SUMO protein family and functions in a manner similar to ubiquitin. However, unlike ubiquitin which targets proteins for degradation, SUMO-1 protein participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. Recombinant human SUMO1 protein was expressed in E.coli and purified by using conventional chromatography. |
| Supplier | ARP |
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