| Product Name | SUMO-2, 1-93aa, Human, Recombinant |
|---|---|
| Description | Small ubiquitin-related modifier 2 (SUMO-2) is a member of the SUMO protein family and functions in a manner similar to ubiquitin. However, unlike ubiquitin which targets proteins for degradation, SUMO-2 protein is involved in diverse cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. This protein is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Recombinant human SUMO2 protein was expressed in E.coli and purified by using conventional chromatography. |
| Synonyms | Small ubiquitin-related modifier 2, SUMO-2, SUMO-3, Sentrin-2, HSMT3, SMT3B, SMT3H2, Small ubiquitin-related modifier 2 SMT3 suppressor of mif two 3 homolog 2 (S, cerevisiae), HSMT 3, MGC117191, Sentrin 2, Sentrin2, Small ubiquitin like modifier 2, Small ubiquitin related modifier 2, SMT 3B, SMT3 homolog 2, SMT3 suppressor of mif two 3 homolog 2, Sumo2, Sumo3, Ubiquitin like protein SMT3B. |
| Host | E. coli |
| Molecular Weight | 36.1kDa (302aa), confirmed by MALDI-TOF. |
| Amino Acid Sequence | MADEKPKEGV KTENNDHINL KVAGQDGSVV QFKIKRHTPL SKLMKAYCER QGLSMRQIRF RFDGQPINET DTPAQLEMED EDTIDVFQQQ TGG |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol. |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| Purity | > 95% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Huang WC., et al. (2004). Eur J Biochem. 271(20):4114-22. Tatham MH., et al. (2001). J Biol Chem. 276(38):35368-74. |
| Background | Small ubiquitin-related modifier 2 (SUMO-2) is a member of the SUMO protein family and functions in a manner similar to ubiquitin. However, unlike ubiquitin which targets proteins for degradation, SUMO-2 protein is involved in diverse cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. This protein is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Recombinant human SUMO2 protein was expressed in E.coli and purified by using conventional chromatography. |
| Supplier | ARP |
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