| Product Name | Anti-Cytokeratins/Keratins Type I & II Monoclonal Antibody |
|---|---|
| Description | Polypeptide reacting: Mr 40 000, Mr 48 000 and Mr 50 000 polypeptides of human epithelial proteins (keratins nos. K19, K16, K14) and most other acidic (type I) keratins (AE1); most basic (type II) keratins (Mr 52 500 - 68 000) of human epithelia (AE3). Mouse Monoclonal Antibody to Keratins Type I & II. Polypeptide reacting: Mr 40 000, Mr 48 000 and Mr 50 000 polypeptides of human epithelial proteins (keratins nos. K19, K16, K14) and most other acidic (type I) keratins (AE1); most basic (type II) keratins (Mr 52 500 - 68 000) of human epithelia (AE3). |
| Clone | AE 1/AE 3 |
| Immunogen | Human epidermal keratin |
| Isotype | All IgG1 |
| Specificity | AE 1/AE 3 represents an excellent marker with a very broad range for distinguishing carcinomas from non-epithelial tumors; reacts with all epithelium-derived tumors and their neoplasms. |
| Reactivity | Gallus, Bovine, Guinea Pig, Human, Mouse, Primate, Rabbit, Rat |
| Applications | WB |
| Form | Purified (Ion-exchange), in PBS containing 1% BSA and 0.1% sodium-azide |
| Storage | 2-8C for immediate use, or at -20C (aliquot) |
| References | Battifora, H., (1984) Cancer 54: 843-848Eichner, R. et al. (1984) J. Cell. Biol. 98,: 1388-1396Garin-Chesa, P.et al. (1986) Am. J. Surg. Pathol. 10: 829-835Nelson, W.G.et al. (1984) Cancer Res. 44 : 1600-1603Nelson, W.G. and Sun T.-T. (1983) J. Cell Biol. 97,: 244-251Moll, R. et al. (1982) Cell 31: 11-24Shi, S.-R. et al. (1984) Am. J. Pathol. 117: 53-63Spagnolo, D. V.,et al. (1985) Am J. Clin. Pathol. 84: 697-704Sun, T.-T. et al. (1984) The Cancer Cell 1: 169-176Sun, T.-T. et al. (1983) J. Invest. Dermatol. 81: 109-115Sun, T.-T. et al. (1985)A review. In: Intermediate Filaments. The New York Acad. Sci. (E. Wang et al. eds.) 455: 307-329Tseng, S.C.G. et al. (1982) Cell 30: 361-372Woodcock-Mitchell, J.,et al. (1982) J. Cell Biol. 95: 580-588Weiss, R.A. et al. (1984) J. Cell Biol. 98: 1397-1406Weiss, R.A. et al. (1983) J. Invest. Dermatol. 81: 2279-2286 |
| Supplier | ARP |
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