Anti-IP3 Receptor Type 1 (IP3R3) Monoclonal Antibody

Antibodies, Monoclonal Antibodies
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Product Name Anti-IP3 Receptor Type 1 (IP3R3) Monoclonal Antibody
Description Mouse monoclonal antibody to IP3 Receptor Type 3 (IP3R3)
Synonyms IP3 Receptor Type 3 antibody, anti-IP3 Receptor Type 3 antibody, anti IP3R3 antibody, IP3R3
Clone IP3R.3
Immunogen Short synthetic polypeptide which recognizes the C-terminus cytoplasmic domain for IP3 receptor type 3 (IP3R3) and shares no sequence homology with other IP3 receptor subtypes (e.g. IP3R1, type 1 or IP3R2, type 2)
Specificity This antibody reacts IP3 receptor type 3 (a homotetramer, 260 kDa) isolated from a variety of cell types (e.g. lymphocytes, macrophages, granulocytes, fibroblasts, epithelial, endothelial cells, skeletal muscle, cardiac muscle and brain tissues). Note: The IP3 Receptor antigen might be susceptible to proteolytic degradation. We recommend to use protease inhibitors during sample preparation.
Form Purified IgG, in 10mM sodium phosphate, 150mM NaCl, 0.01% NaN3, pH 7.5
Reactivity Bovine cells/tissues, Human, Mouse, Rat
Applications ELISA, FC, IF, IP, WB
Working Dilutions 1:100 - 1:200 for Immunofluorescence; 1:500 - 1:1000 for Immunoblotting; 1:250 - 1:500 for ELISA. Optimal dilution should be performed by user.
Isotype Mouse IgG2b
Storage 2-8C for immediate use, or at -20C (aliquot)
Intended Use For Research Use Only
References Sugiyama T. et al. (1994) FEBS Letters 354: 149-154Bourguignon, LYW. et al. (1996) Mol. Biol. Cell in press

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