| Product Name | Anti-Mucin 2 Monoclonal Antibody |
|---|---|
| Description | This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. The antibody reacts with mucin from small and large intestine and to a weaker extent with salivary and breast epithelia. Stomach, pancreas, kidney and ovary epithelia are negative. |
| Synonyms | MLP, SMUC, MUC-2 |
| Clone | MUC-2/Ccp58 |
| Immunogen | Synthetic human MUC-2 (MI-29) peptide |
| Isotype | IgG1 |
| Specificity | Positive reaction of gastric cancer and colon cancer. The antigen is localized in the cytoplasm |
| Reactivity | Human |
| Applications | IF, IHC |
| Form | Hybridoma culture Supernatant |
| Storage | 2-8C |
| References | Xing, XP. et al.(1992) J. Natl. Cancer Inst 84: 699-703 |
| Supplier | ARP |
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