| Product Name | Anti-Serotonin Antibody Polyclonal Antibody |
|---|---|
| Description | This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. |
| Synonyms | HTT, 5HTT, OCD1, SERT, 5-HTT, SERT1, hSERT, 5-HTTLPR |
| Immunogen | Serotonin/Ovalbumin |
| Specificity | The polyclonal antibody to serotonin can be used to differentiate tumors of serotoninergic origin. The antigen localization is cytoplasmic. |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IF, IHC, WB |
| Form | Serum containing 0.1% sodium azide |
| Storage | 2-8C for immediate use, or at -20C (aliquot) |
| References | Arends JW et al. (1986) J Pathology 149: 97-102 |
| Supplier | ARP |
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