BCL2L2, 1-172aa, Human

Catalog
01-2064-L2
$0.00
-
+
Proteins, Recombinant
Questions? Contact Us
More Information
Product Name BCL2L2, 1-172aa, Human
Background BCL2-like protein 2, also known as BCL2L2, is a member of the Bcl-2 family of proteins that regulates outer mitochondrial membrane permeability. BCL2L2 is an anti apoptotic member that prevents release of cytochrome c from the mitochondria intermembrane space into the cytosol. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. It is required for normal sperm maturation. Recombinant human BCL2L2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms Apoptosis regulator Bcl-W, BCLW, BCL2-like protein 2 Apoptosis regulator BCL W, BCL 2 Like 2, Bcl 2 like 2 protein, Bcl 2L2, bcl w, Bcl2 L2, BCL2 like 2, BCL2 like 2 protein, KIAA0271.
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MATPASAPDT RALVADFVGY KLRQKGYVCG AGPGEGPAAD PLHQAMRAAG DEFETRFRRT FSDLAAQLHV TPGSAQQRFT QVSDELFQGG PNWGRLVAFF VFGAALCAES VNKEMEPLVG QVQEWMVAYL ETRLADWIHS SGGWAEFTAL YGDGALEEAR RLREGNWASV RT
Molecular Weight 36.9 kDa (336aa), confirmed by MALDI-TOF.
Concentration 0.5 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1 M NaCl.
Purity > 95% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_004041
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Zhu X., et al. (2004) J Neurochem. 89(5):1233-40.
Kromer G., et al. (1997) Nature Med. 3:614.

All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.

Hi, have questions?

An ARP Customer Service Representative is happy to help!

or Call (800) 832-2611