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|Product Name||CRABP1, 1-137aa, Human, Recombinant|
|Background||CRABP1, also known as cellular retinoic acid-binding protein 1, is a member of specific carrier proteins for members of the vitamin A family. This protein is assumed to play an important role in retinoic acid-mediated differentiation and proliferation processes. CRABP1 is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid. It is constitutively expressed and is believed to have different functions in the cell than the related CRABP2. Recombinant CRABP1 protein was expressed in E.coli and purified by using conventional chromatography techniques.|
|Synonyms||CRABP, CRABP-I, CRABPI, RBP5, Cellular retinoic acid binding protein 1 CRABP 1, CRABP I, RBP 5, Retinoic acid binding protein I cellular.|
|Amino Acid Sequence||MPNFAGTWKM RSSENFDELL KALGVNAMLR KVAVAAASKP HVEIRQDGDQ FYIKTSTTVR TTEINFKVGE GFEEETVDGR KCRSLATWEN ENKIHCTQTL LEGDGPKTYW TRELANDELI LTFGADDVVC TRIYVRE|
|Molecular Weight||31.5 kDa (277aa), confirmed by MALDI-TOF.|
|Concentration||1 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.|
|Purity||> 95% by SDS-PAGE|
|NCBI Accession #||NP_004369|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Wang L, et al. (1997) J Biol Chem, 272(3):1541-7.
Astrom A, et al. (1991) J Biol Chem, 266(26):17662-6.
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