CRABP1, 1-137aa, Human, Recombinant

Proteins, Recombinant
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Product Name CRABP1, 1-137aa, Human, Recombinant
Background CRABP1, also known as cellular retinoic acid-binding protein 1, is a member of specific carrier proteins for members of the vitamin A family. This protein is assumed to play an important role in retinoic acid-mediated differentiation and proliferation processes. CRABP1 is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid. It is constitutively expressed and is believed to have different functions in the cell than the related CRABP2. Recombinant CRABP1 protein was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms CRABP, CRABP-I, CRABPI, RBP5, Cellular retinoic acid binding protein 1 CRABP 1, CRABP I, RBP 5, Retinoic acid binding protein I cellular.
Species Human
Molecular Weight 31.5 kDa (277aa), confirmed by MALDI-TOF.
Concentration 1 mg/ml (determined by Bradford assay)
Form Liquid, in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.
Purity > 95% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_004369
Host E.coli
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Wang L, et al. (1997) J Biol Chem, 272(3):1541-7.
Astrom A, et al. (1991) J Biol Chem, 266(26):17662-6.

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