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|Product Name||DGCR6L, 1-220aa, Human|
|Background||DGCR6L is a protein that shares homology with the Drosophila gonadal protein, expressed in gonadal tissues and germ cells, and with the human laminin gamma-1 chain that functions in cell attachment and migration. This protein is located in a region of chromosome 22 implicated in the DiGeorge syndrome, one facet of a broader collection of anomalies referred to as the CATCH 22 syndrome. Recombinant human DGCR6L protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
|Synonyms||Gem-associated protein 6, gem (nuclear organelle) associated protein 6|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGSMERYAAA LEEVADGARQ QERHYQLLSA LQSLVKELPS SFQQRLSYTT LSDLALALLD GTVFEIVQGL LEIQHLTEKS LYNQRLRLQN EHRVLRQALR QKHQEAQQAC RPHNLPVVQA AQQRELEAVE HRIREEQRAM DQKIILELDR KVADQQSTLE KAGVAGFYVT TNPQELMLQM NLLELIRKLQ QRGCRAGNAA LGLGGPWQSP AAQCDQKGSP VPP|
|Molecular Weight||39.7 kDa(372aa) confirmed by MALDI-TOF
(Molecular size on SDS-PAGE will appear higher)
|Concentration||0.5 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl, 1mM DTT|
|Purity||> 85% by SDS-PAGE|
|NCBI Accession #||NP_150282|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Li,X., et al. (2010) Int. J. Biochem. Cell Biol. 42 (1), 70-79
Pfuhl,T., et al. (2005) Hum. Genet. 117 (1), 70-80
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