HAPLN1, 16-354aa, Human

Catalog
01-P2746
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Proteins, Recombinant
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Product Name HAPLN1, 16-354aa, Human
Background : HAPLN1 belongs to the HAPLN family. It contains 1 Ig-like V-type (immunoglobulin-like) domain and contains 2 Link domains. This protein stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix. Recombinant human HAPLN1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Synonyms Hyaluronan and proteoglycan link protein 1 precursor, CRTL1
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSDHLSDNY TLDHDRAIHI QAENGPHLLV EAEQAKVFSH RGGNVTLPCK FYRDPTAFGS GIHKIRIKWT KLTSDYLKEV DVFVSMGYHK KTYGGYQGRV FLKGGSDSDA SLVITDLTLE DYGRYKCEVI EGLEDDTVVV ALDLQGVVFP YFPRLGRYNL NFHEAQQACL DQDAVIASFD QLYDAWRGGL DWCNAGWLSD GSVQYPITKP REPCGGQNTV PGVRNYGFWD KDKSRYDVFC FTSNFNGRFY YLIHPTKLTY DEAVQACLND GAQIAKVGQI FAAWKILGYD RCDAGWLADG SVRYPISRPR RRCSPTEAAV RFVGFPDKKH KLYGVYCFRA YN
Molecular Weight 54.7kDa (482aa)
Concentration Chain D., et al. (1991) FEBS Lett. 285: 251-256.
Cherny R C., et al. (1993) J Biol Chem. 268: 9725-9729.
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
Purity > 80% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_001875
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Naba,A, et al. (2012) Mol. Cell Proteomics 11 (4), M111
Lin,Z., et al. (2012) Nat. Genet. 44 (1), 73-77

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