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|Product Name||HAPLN1, 16-354aa, Human|
|Background||: HAPLN1 belongs to the HAPLN family. It contains 1 Ig-like V-type (immunoglobulin-like) domain and contains 2 Link domains. This protein stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix. Recombinant human HAPLN1 protein, fused to His-tag at N-terminus, was expressed in E.coli.|
|Synonyms||Hyaluronan and proteoglycan link protein 1 precursor, CRTL1|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGSDHLSDNY TLDHDRAIHI QAENGPHLLV EAEQAKVFSH RGGNVTLPCK FYRDPTAFGS GIHKIRIKWT KLTSDYLKEV DVFVSMGYHK KTYGGYQGRV FLKGGSDSDA SLVITDLTLE DYGRYKCEVI EGLEDDTVVV ALDLQGVVFP YFPRLGRYNL NFHEAQQACL DQDAVIASFD QLYDAWRGGL DWCNAGWLSD GSVQYPITKP REPCGGQNTV PGVRNYGFWD KDKSRYDVFC FTSNFNGRFY YLIHPTKLTY DEAVQACLND GAQIAKVGQI FAAWKILGYD RCDAGWLADG SVRYPISRPR RRCSPTEAAV RFVGFPDKKH KLYGVYCFRA YN|
|Molecular Weight||54.7kDa (482aa)|
|Concentration||Chain D., et al. (1991) FEBS Lett. 285: 251-256.
Cherny R C., et al. (1993) J Biol Chem. 268: 9725-9729.
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol|
|Purity||> 80% by SDS-PAGE|
|NCBI Accession #||NP_001875|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Naba,A, et al. (2012) Mol. Cell Proteomics 11 (4), M111
Lin,Z., et al. (2012) Nat. Genet. 44 (1), 73-77
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