HSPA13, 23-471aa, Human

Catalog
01-2045-13
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Proteins, Recombinant
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Product Name HSPA13, 23-471aa, Human
Background HSPA13, also known as STCH, is a member of the heat shock protein 70 family and is found associated with microsomes. Members of this protein family play a role in the processing of cytosolic and secretory proteins, as well as in the removal of denatured or incorrectly-folded proteins. HSPA13 has been found to interact with PLIC-1 and PLIC-2, proteins involved in the signaling connection between the membrane receptors for thrombospondin and the cytoskeleton. Recombinant human HSPA13 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms Heat shock protein 70kDa family member 13, STCH
Species Human
Amino Acid Sequence MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSELEM QQYLPLPTPK VIGIDLGTTY CSVGVFFPGT GKVKVIPDEN GHISIPSMVS FTDNDVYVGY ESVELADSNP QNTIYDAKRF IGKIFTAEEL EAEIGRYPFK VLNKNGMVEF SVTSNETITV SPEYVGSRLL LKLKEMAEAY LGMPVANAVI SVPAEFDLKQ RNSTIEAANL AGLKILRVIN EPTAAAMAYG LHKADVFHVL VIDLGGGTLD VSLLNKQGGM FLTRAMSGNN KLGGQDFNQR LLQYLYKQIY QTYGFVPSRK EEIHRLRQAV EMVKLNLTLH QSAQLSVLLT VEEQDRKEPH SSDTELPKDK LSSADDHRVN SGFGRGLSDK KSGESQVLFE TEISRKLFDT LNEDLFQKIL VPIQQVLKEG HLEKTEIDEV VLVGGSTRIP RIRQVIQEFF GKDPNTSVDP DLAVVTGVAI QAGIDGGFWP LQVSALEIPN KHLQKTNFN
Molecular Weight 16.7 kDa (149aa) confirmed by MALDI-TOF
Concentration 0.5 mg/ml (determined by BCA assay)
Form Liquid, in 20 mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl, 1mM DTT, 10% glycerol
Purity > 95% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # AAH36370
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Lim J., et al. (2006) Cell. 125(4):801-14.
Rual JF., et al. (2005) Nature. 437(7062):1173-8.

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