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|Product Name||ID1, 1-155aa, Human|
|Background||ID1 is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Recombinant human ID1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
|Synonyms||DNA-binding protein inhibitor ID-1, bHLHb24, ID|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGSMKVASGS TATAAAGPSC ALKAGKTASG AGEVVRCLSE QSVAISRCAG GAGARLPALL DEQQVNVLLY DMNGCYSRLK ELVPTLPQNR KVSKVEILQH VIDYIRDLQL ELNSESEVGT PGGRGLPVRA PLSTLNGEIS ALTAEAACVP ADDRILCR|
|Molecular Weight||21.9kDa (218aa) confirmed by MALDI-TOF
(Molecular weight on SDS-PAGE will appear higher)
|Concentration||0.25 mg/ml (determined by BCA assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol|
|Purity||> 85% by SDS-PAGE|
|NCBI Accession #||NP_002156|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Deed R.W., et al. (1994) Biochim. Biophys. Acta. 1219:160-162
Hara E., et al. (1994) J. Biol. Chem. 269:2139-2145
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