ID2, 1-134aa, Human

Catalog
01-P1991
$0.00
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Proteins, Recombinant
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More Information
Product Name ID2, 1-134aa, Human
Background ID2 belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. Recombinant human ID2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Synonyms Inhibitor of DNA binding 2, bHLHb26, GIG8, ID2A, ID2H, MGC26389
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MKAFSPVRSV RKNSLSDHSL GISRSKTPVD DPMSLLYNMN DCYSKLKELV PSIPQNKKVS KMEILQHVID YILDLQIALD SHPTIVSLHH QRPGQNQASR TPLTTLNTDI SILSLQASEF PSELMSNDSK ALCG
Molecular Weight 16.8 kDa(155aa) confirmed by MALDI-TOF
Concentration 0.5 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl
Purity > 85% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_002157
Host E.coli
Tag His-tag
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.
Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Hara E. et al. (1994) J Biol Chem. 269:2139-2145.
Langlands Ket al. (1997) J Biol Chem. 272:19785-19793.

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