ID2, 1-134aa, Human

Proteins, Recombinant
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Product Name ID2, 1-134aa, Human
Background ID2 belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. Recombinant human ID2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Synonyms Inhibitor of DNA binding 2, bHLHb26, GIG8, ID2A, ID2H, MGC26389
Species Human
Molecular Weight 16.8 kDa(155aa) confirmed by MALDI-TOF
Concentration 0.5 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl
Purity > 85% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_002157
Host E.coli
Tag His-tag
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.
Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Hara E. et al. (1994) J Biol Chem. 269:2139-2145.
Langlands Ket al. (1997) J Biol Chem. 272:19785-19793.

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