| Product Name | MAT II beta, 1-323aa, Human |
|---|---|
| Description | Methionine adenosyltransferase II, beta (MAT II beta) belongs to the methionine adenosyltransferase (MAT) family. MAT II beta catalyzes the biosynthesis of S-adenosylmethionine from methionine and ATP. This protein is the regulatory beta subunit of MAT. Its expression in hepatoma cell lines may lead to increase DNA synthesis and thereby participate to cell proliferation. Recombinant human MAT II beta was expressed in E.coli and purified by using conventional chromatography techniques. |
| Synonyms | MAT2B, TGR, Methionine adenosyltransferase II, beta 1110064C04Rik, 2410018D16Rik, AI182287, AU022853, MAT II, MATIIbeta, MGC12237, Nbla02999, SDR23E1, Beta regulatory subunit of methionine adenosyltransferase, dTDP 4 keto 6 deoxy D glucose 4 reductase, MAT II beta, Methionine adenosyltransferase 2 beta subunit, Methionine adenosyltransferase 2 subunit beta, Methionine adenosyltransferase II beta, OTTMUSP00000005600, Putative protein product of Nbla02999, RP23-382C18.2, Short chain dehydrogenase/reductase family 23E member 1, TGR |
| Host | E.coli |
| Molecular Weight | 47.6 kDa (421aa), confirmed by MALDI-TOF. |
| Amino Acid Sequence | MPEMPEDMEQ EEVNIPNRRV LVTGATGLLG RAVHKEFQQN NWHAVGCGFR RARPKFEQVN LLDSNAVHHI IHDFQPHVIV HCAAERRPDV VENQPDAASQ LNVDASGNLA KEAAAVGAFL IYISSDYVFD GTNPPYREED IPAPLNLYGK TKLDGEKAVL ENNLGAAVLR IPILYGEVEK LEESAVTVMF DKVQFSNKSA NMDHWQQRFP THVKDVATVC RQLAEKRMLD PSIKGTFHWS GNEQMTKYEM ACAIADAFNL PSSHLRPITD SPVLGAQRPR NTQLDCSKLE TLGIGQRTPF RIGIKESLWP FLIDKRWRQT VFH |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT. |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
| References |
Steele W., et al. (2005) Reprod Biomed Online. 10(6):755-66. LeGros L., et al. (2001) J Biol Chem. 276(27):24918-24. |
| Supplier | ARP |
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