MSRB3, 21-185aa, Human

Proteins, Recombinant
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Product Name MSRB3, 21-185aa, Human
Background Methionine sulfoxide reductase B3, also known as MSRB3, belongs to the methionine sulfoxide reductases (MSR) family proteins. MSRs are thought to protect against reactive oxygen species-induced oxidative damage in many organs, including the most environmentally exposed organ, human skin. MSRB3 plays an important role in cold tolerance by eliminating MetO and ROS that accumulate at the ER during cold acclimation. Recombinant human MSRB3 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms Methionine sulfoxide reductase B3,
Species Human
Molecular Weight 25.8kDa (233aa) confirmed by MALDI-TOF
Concentration 0.5 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 1mM DTT, 100mM NaCl
Purity > 90% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_001026849
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Taunqiaruwinai WM., et al. (2009) Am J Dermatopathol. 31(5):427-31-7.
Kwon SJ., et al. (2007) Plant Cell Physiol. 48(12):1713-23.

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