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|Product Name||PRDX1, 1-199aa, Human, Recombinant|
|Background||PRDX1 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. This protein is also known to be important to protect red blood cells against reactive oxygen species and in tumor prevention. Recombinant human PRDX1, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography techniques.|
|Synonyms||MSP23, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2, Thioredoxin peroxidase 2, Peroxiredoxin 1, PRDX1, Peroxiredoxin 1 Hbp23, Heme binding 23 kDa protein, Paga, Prdx 1, Macrophage 23 Kd stress protein, NKEF A, NkefA, OSF3, Macrophage 23kDa stress protein, PrxI, Tdpx 2, TDX2, Macrophase stress protein 22kDa, TPxA Macrophase stress protein 23 kd, Natural killer cell enhancing factor A, Natural killer enhancing factor A, Osteoblast specific factor 3, Proliferation associated gene A, Proliferation associated protein PAG, Thioredoxin dependent peroxide reductase 2,|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MSSGNAKIGH PAPNFKATAV MPDGQFKDIS LSDYKGKYVV FFFYPLDFTF VCPTEIIAFS DRAEEFKKLN CQVIGASVDS HFCHLAWVNT PKKQGGLGPM NIPLVSDPKR TIAQDYGVLK ADEGISFRGL FIIDDKGILR QITVNDLPVG RSVDETLRLV QAFQFTDKHG EVCPAGWKPG SDTIKPDVQK SKEYFSKQK|
|Molecular Weight||18 kDa (167 aa), confirmed by MALDI-TOF.|
|Concentration||1 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris pH 8.0, 2mM EDTA, 1mM DTT, 10% glycerol|
|Purity||> 90% by SDS-PAGE|
|NCBI Accession #||NP_002565|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Iraqui I., et al. (2008) Cancer Res. 68(4):1055-63.
Parmigiani RB., et al. (2008) Proc Natl Acad Sci U S A. 105(28):9633-8.
Kim JH., et al. (2008) Clin Cancer Res. 14(8):2326-33.
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