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|Product Name||RAC2, 1-189aa, Human, Recombinant|
|Background||Rac2 is a small signaling G protein (more specifically a GTPase), and is a member of the Rac subfamily of the family Rho family of GTPases. Rac proteins play important roles in multiple cellular events, including actin cytoskeletal organization, cell proliferation and survival, cell cycle progression, and gene transcription regulation. Recombinant human RAC2 was expressed in E.coli and purified by using conventional chromatography techniques.|
|Synonyms||EN-7, Gx, HSPC022, Ras-related C3 botulinum toxin substrate 2, EN 7, EN7, HSPC 022, p21 Rac 2, p21 Rac2, p21Rac2, RAC 2, Ras related C3 botulinum toxin substrate 2, Ras related C3 botulinum toxin substrate 3, Rho family small GTP binding protein Rac 2, Rho family small GTP binding protein Rac2, Small G protein.|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDSKP VNLGLWDTAG QEDYDRLRPL SYPQTDVFLI CFSLVSPASY ENVRAKWFPE VRHHCPSTPI ILVGTKLDLR DDKDTIEKLK EKKLAPITYP QGLALAKEID SVKYLECSAL TQRGLKTVFD EAIRAVLCPQ PTRQQKRAC|
|Molecular Weight||14.5 kDa (123aa), confirmed by MALDI-TOF.|
|Concentration||0.5 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, and 20% glycerol.|
|Purity||> 95% by SDS-PAGE|
|NCBI Accession #||NP_002863|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Ambruso DR., et al. (2000) Proc Natl Acad Sci U S A. 97(9):4654-9.
Faure J., et al. (2001) Biochimie. 83(5):409-14.
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