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|Product Name||RBP7, 1-134aa, Human|
|Background||RBP7, also known as CRBP4, belongs to a superfamily of small cytoplasmic proteins which interact with hydrophobic ligands. RBP7 is cytoplasmic protein that, like CRBP I and CRBP II, form beta-barrel structures and participates in the intracellular transport of retinol. RBP7 is a recently identified cellular retinol carrier, expressed in the kidney, heart and transverse colon in humans. Recombinant human RBP7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
|Synonyms||Retinoid-binding protein 7, CRBP4, CRBPIV, MGC70641|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MPADLSGTWT LLSSDNFEGY MLALGIDFAT RKIAKLLKPQ KVIEQNGDSF TIHTNSSLRN YFVKFKVGEE FDEDNRGLDN RKCKSLVIWD NDRLTCIQKG EKKNRGWTHW IEGDKLHLEM FCEGQVCKQT FQRA|
|Molecular Weight||25 kDa (226aa), confirmed by MALDI-TOF|
|Concentration||1 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT.|
|Purity||> 90% by SDS-PAGE|
|NCBI Accession #||NP_443192|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Aoki T., et al. (2009) Clin Exp Allergy. 39(2):213-21.
Sampath V., et al. (2008) J Biol Chem. 283(7):3923-31.
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