RGS19, 1-217aa, Human

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01-1796-19
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Proteins, Recombinant
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Product Name RGS19, 1-217aa, Human
Background RGS19, also known as Regulator of G-protein signaling 19, belongs to RGS (regulator of G protein signaling) family and negatively regulates G protein coupled receptor signaling. This protein specifically interacts with heterotrimeric GTP-binding protein G alpha i3 (GAI3). Recombinant human RGS19 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Synonyms Regulator of G-protein signaling 19, GAIP, GNAI3IP
Species Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MPTPHEAEKQ ITGPEEADRP PSMSSHDTAS PAAPSRNPCC LCWCCCCSCS WNQERRRAWQ ASRESKLQPL PSCEVCATPS PEEVQSWAQS FDKLMHSPAG RSVFRAFLRT EYSEENMLFW LACEELKAEA NQHVVDEKAR LIYEDYVSIL SPKEVSLDSR VREGINKKMQ EPSAHTFDDA QLQIYTLMHR DSYPRFLSSP TYRALLLQGP SQSSSEA
Molecular Weight 15.8kDa (144aa) confirmed by MALDI-TOF
Concentration 0.5mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 5mM DTT, 100mM NaCl
Purity > 90% by SDS-PAGE
Applications SDS-PAGE
NCBI Accession # NP_001034556
Host E.coli
Tag His-tag
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Intended Use For Research Use Only
References Wong YH., et al. (2010) Cell Signal. 22(11):1700-7.
Farquhar MG., et al (1995) Proc Natl Acad Sci U S A. 92(25):11916-20.

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