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|Product Name||RGS21, 1-152aa, Human|
|Background||Regulator of G-protein signaling 21, also known as RGS21, is a RGS family member and regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Recombinant human RGS21 human, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
|Synonyms||Regulator of G-protein signaling 21,|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGSHMPVKCC FYRSPTAETM TWSENMDTLL ANQAGLDAFR IFLKSEFSEE NVEFWLACED FKKTKNADKI ASKAKMIYSE FIEADAPKEI NIDFGTRDLI SKNIAEPTLK CFDEAQKLIY CLMAKDSFPR FLKSEIYKKL VNSQQVPNHK KWLPFL|
|Molecular Weight||61.4 kDa (566aa)|
|Concentration||1.0 mg/ml (determined by BCA assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT, 0.1mM PMSF|
|Purity||> 90% by SDS-PAGE|
|NCBI Accession #||NP_001034241|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Li X., et al. (2005) Acta Biochim Pol. 52(4):943-6.
Von Buchholtz L., et al. (2004) Eur J Neurosci. 19(6):1535-44.
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