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|Product Name||TSSK2, 1-358aa, Human|
|Background||TSSK2 is a testis-specific serine/threonine-protein kinase required during spermatid development. This protein phosphorylates TSKS at 'Ser-288' and SPAG16. TSSK2 involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, it is required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body. Recombinant human TSSK2 protein, fused to His-tag at N-terminus, was expressed in E.coli.|
|Synonyms||Testis-specific serine/threonine-protein kinase 2, DGS-G, SPOGA2, STK22B, TSK2|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGSMDDATVL RKKGYIVGIN LGKGSYAKVK SAYSERLKFN VAVKIIDRKK TPTDFVERFL PREMDILATV NHGSIIKTYE IFETSDGRIY IIMELGVQGD LLEFIKCQGA LHEDVARKMF RQLSSAVKYC HDLDIVHRDL KCENLLLDKD FNIKLSDFGF SKRCLRDSNG RIILSKTFCG SAAYAAPEVL QSIPYQPKVY DIWSLGVILY IMVCGSMPYD DSDIRKMLRI QKEHRVDFPR SKNLTCECKD LIYRMLQPDV SQRLHIDEIL SHSWLQPPKP KATSSASFKR EGEGKYRAEC KLDTKTGLRP DHRPDHKLGA KTQHRLLVVP ENENRMEDRL AETSRAKDHH ISGAEVGKAS T|
|Molecular Weight||37.5 kDa (330aa)|
|Concentration||1 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol|
|Purity||> 85% by SDS-PAGE|
|NCBI Accession #||NP_443732|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Kueng P, Nikolova Z, et al. (1997). J Cell Biol. 139(7):1851-9.|
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