Chicken PRELI domain-containing protein 1, mitochondrial (PRELID1) ELISA Kit

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AE26063CH
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Product Name Chicken PRELI domain-containing protein 1, mitochondrial (PRELID1) ELISA Kit
Description The predicted 219-amino acid human protein is 85% identical to the avian protein. PX19 contains 2 alpha helices with amphipathic domains in opposite orientation, and the LEA motifs (A/TAEKAK) are clustered within this region. Northern blot analysis detected 1.0- and 1.2-kb transcripts predominantly in fetal liver, with much lower levels in other fetal tissues. Expression was significantly reduced in adult liver, but was higher in other adult organs. Expression was low in bone marrow and thymus, but high in adult spleen, lymph node, and peripheral blood leukocytes. Further analysis of B-cell lines indicated that expression was higher in mature B cells, predominantly from germinal centers, and absent in progenitor and precursor B-cell lines. This assay has high sensitivity and excellent specificity for detection of Chicken PRELID1. No significant cross-reactivity or interference between Chicken PRELID1 and analogues was observed.
Synonyms CGI-106, MGC87972, PRELI, PX19, protein of relevant evolutionary and lymphoid interest|px19-like protein
Method Sandwich ELISA
Detection Range Request Information
Sensitivity Request Information
Reactivity Chicken
Sample Types Serum, Plasma, Other biological fluids.
Background The predicted 219-amino acid human protein is 85% identical to the avian protein. PX19 contains 2 alpha helices with amphipathic domains in opposite orientation, and the LEA motifs (A/TAEKAK) are clustered within this region.
Northern blot analysis detected 1.0- and 1.2-kb transcripts predominantly in fetal liver, with much lower levels in other fetal tissues. Expression was significantly reduced in adult liver, but was higher in other adult organs. Expression was low in bone marrow and thymus, but high in adult spleen, lymph node, and peripheral blood leukocytes. Further analysis of B-cell lines indicated that expression was higher in mature B cells, predominantly from germinal centers, and absent in progenitor and precursor B-cell lines.
Supplier Abebio

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