Cow DNA-directed RNA polymerase II subunit RPB3 (POLR2C) ELISA Kit
| Product Name | Cow DNA-directed RNA polymerase II subunit RPB3 (POLR2C) ELISA Kit |
|---|---|
| Description | POLR2C encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21. The deduced 275-amino acid human POLR2C protein, termed RPB33 by the authors, shares 45% sequence identity with the yeast homolog RPB3. POLR2C contains a single cysteine-rich region. Northern blot analysis of HeLa cell mRNA detected an approximately 1.8-kb POLR2C doublet. This assay has high sensitivity and excellent specificity for detection of Bovine POLR2C. No significant cross-reactivity or interference between Bovine POLR2C and analogues was observed. |
| Synonyms | RPB3, RPB31, hRPB33, hsRPB3, DNA directed RNA polymerase II polypeptide C|RNA polymerase II subunit 3 |
| Method | Sandwich ELISA |
| Detection Range | Request Information |
| Sensitivity | Request Information |
| Reactivity | Bovine |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background |
POLR2C encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21. The deduced 275-amino acid human POLR2C protein, termed RPB33 by the authors, shares 45% sequence identity with the yeast homolog RPB3. POLR2C contains a single cysteine-rich region. Northern blot analysis of HeLa cell mRNA detected an approximately 1.8-kb POLR2C doublet. |
| Supplier | Abebio |
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