Cow Mitochondrial import receptor subunit TOM40B (TOMM40L) ELISA Kit
| Product Name | Cow Mitochondrial import receptor subunit TOM40B (TOMM40L) ELISA Kit |
|---|---|
| Description | TOMM40L belongs to the Tom40 family. Potential channel-forming protein implicated in import of protein precursors into mitochondria. TOMM40 is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for protein import into mitochondria.Extraction and antibody-accessibility studies suggested that Tomm40 is embedded within the mitochondrial membrane.Tomm40 was associated with a 400-kD complex containing the mitochondrial import receptors Tom20 and Tom22 and several smaller components. Mitochondria-targeted preproteins interacted with the Tomm40-containing complex during their transit to the mitochondrial matrix, and immunodepletion of Tomm40 caused the loss of preprotein import activity. This assay has high sensitivity and excellent specificity for detection of Bovine TOMM40L. No significant cross-reactivity or interference between Bovine TOMM40L and analogues was observed. |
| Synonyms | FLJ12770, RP11-297K8.10, TOMM40B, OTTHUMP00000032243|translocase of outer mitochondrial membrane 40 homolog-like |
| Method | Sandwich ELISA |
| Detection Range | Request Information |
| Sensitivity | Request Information |
| Reactivity | Bovine |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | TOMM40L belongs to the Tom40 family. Potential channel-forming protein implicated in import of protein precursors into mitochondria. TOMM40 is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for protein import into mitochondria.Extraction and antibody-accessibility studies suggested that Tomm40 is embedded within the mitochondrial membrane.Tomm40 was associated with a 400-kD complex containing the mitochondrial import receptors Tom20 and Tom22 and several smaller components. Mitochondria-targeted preproteins interacted with the Tomm40-containing complex during their transit to the mitochondrial matrix, and immunodepletion of Tomm40 caused the loss of preprotein import activity. |
| Supplier | Abebio |
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