| Product Name | Bovine Paired box protein Pax-6 (PAX6) ELISA Kit |
|---|---|
| Description | Bovine Paired box protein Pax-6 (PAX6) ELISA Kit has high sensitivity and excellent specificity for detection of Bovine PAX6. No significant cross-reactivity or interference between Bovine PAX6 and analogues was observed. PAX6 is the most researched of the Pax genes and appears throughout the literature as a "master control" gene for the development of eyes and other sensory organs, certain neural and epidermal tissues as well as other homologous structures, usually derived from ectodermal tissues. This transcription factor is most famous for its use in the interspecifically induced expression of ectopic eyes and is of medical importance because heterozygous mutants produce a wide spectrum of ocular defects such as Aniridia in humans. PAX6 protein function is highly conserved across bilaterian species, for instance mouse PAX6 can trigger eye development in Drosophila melanogaster. This Bovine Paired box protein Pax-6 (PAX6) ELISA Kit employs a two-site sandwich ELISA to quantitate PAX6 in samples. An antibody specific for PAX6 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyPAX6 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PAX6 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PAX6 bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Synonyms | PAX6, AN, AN2, D11S812E, MGC17209, MGDA, WAGR, OTTHUMP00000038834, OTTHUMP00000038836, OTTHUMP00000038837, OTTHUMP00000038838, OTTHUMP00000038839, OTTHUMP00000038840, paired box gene 6, paired box homeotic gene- |
| Method | Sandwich ELISA |
| Detection Range | Please inquire |
| Sensitivity | Please inquire |
| Reactivity | Bovine |
| Sample Types | Cell culture supernatants, Serum, Plasma, Other biological fluids |
| Gene Id | 286857 |
| Storage | 2-8°C |
| Background |
PAX6 is the most researched of the Pax genes and appears throughout the literature as a "master control" gene for the development of eyes and other sensory organs, certain neural and epidermal tissues as well as other homologous structures, usually derived from ectodermal tissues. This transcription factor is most famous for its use in the interspecifically induced expression of ectopic eyes and is of medical importance because heterozygous mutants produce a wide spectrum of ocular defects such as Aniridia in humans. PAX6 protein function is highly conserved across bilaterian species, for instance mouse PAX6 can trigger eye development in Drosophila melanogaster. |
| Supplier | Abbkine |
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