Bovine Proline dehydrogenase 1, mitochondrial (PRODH) ELISA Kit

Category: Assay Kits
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KTE10171
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Product Name Bovine Proline dehydrogenase 1, mitochondrial (PRODH) ELISA Kit
Description Bovine Proline dehydrogenase 1, mitochondrial (PRODH) ELISA Kit has high sensitivity and excellent specificity for detection of Bovine PRODH. No significant cross-reactivity or interference between Bovine PRODH and analogues was observed. Proline dehydrogenase 1, mitochondrial (PRODH) encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in PRODH are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). PRODH is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for PRODH. This Bovine Proline dehydrogenase 1, mitochondrial (PRODH) ELISA Kit employs a two-site sandwich ELISA to quantitate PRODH in samples. An antibody specific for PRODH has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyPRODH present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PRODH is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PRODH bound in the initial step. The color development is stopped and the intensity of the color is measured.
Synonyms PRODH, FLJ33744, HSPOX2, MGC148078, MGC148079, PIG6, POX, PRODH1, PRODH2, SCZD4, TP53I6, proline dehydrogenase 1, proline oxidase 2, proline oxidase, mitochondrial, tumor protein p53 inducible protein 6
Method Sandwich ELISA
Detection Range Please inquire
Sensitivity Please inquire
Reactivity Bovine
Sample Types Cell culture supernatants, Serum, Plasma, Other biological fluids
Gene Id 505094
Storage 2-8°C
Background Proline dehydrogenase 1, mitochondrial (PRODH) encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in PRODH are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). PRODH is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for PRODH.
Supplier Abbkine

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