Bovine Protein tyrosine phosphatase type IVA 3 (PTP4A3) ELISA Kit
| Product Name | Bovine Protein tyrosine phosphatase type IVA 3 (PTP4A3) ELISA Kit |
|---|---|
| Description | Bovine Protein tyrosine phosphatase type IVA 3 (PTP4A3) ELISA Kit has high sensitivity and excellent specificity for detection of Bovine PTP4A3. No significant cross-reactivity or interference between Bovine PTP4A3 and analogues was observed. Protein tyrosine phosphatase type IVA 3 is an enzyme belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist.Mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. Consistently overexpressed in colon cancer metastasis. This Bovine Protein tyrosine phosphatase type IVA 3 (PTP4A3) ELISA Kit employs a two-site sandwich ELISA to quantitate PTP4A3 in samples. An antibody specific for PTP4A3 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyPTP4A3 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PTP4A3 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PTP4A3 bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Synonyms | PTP4A3, PRL-3, PRL-R, PRL3, potentially prenylated protein tyrosine phosphatase |
| Method | Sandwich ELISA |
| Detection Range | Please inquire |
| Sensitivity | Please inquire |
| Reactivity | Bovine |
| Sample Types | Cell culture supernatants, Serum, Plasma, Other biological fluids |
| Gene Id | 100137722 |
| Storage | 2-8°C |
| Background | Protein tyrosine phosphatase type IVA 3 is an enzyme belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist.Mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. Consistently overexpressed in colon cancer metastasis. |
| Supplier | Abbkine |
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